The Coral Symbiomics Lab
Red Sea Research Center
Division of Biological and Environmental Science and Engineering

Publications in 2008

The genome of the model beetle and pest Tribolium castaneum

​Tribolium Genome Sequencing, “The genome of the model beetle and pest Tribolium castaneum,” Nature 452(2008).
Tribolium Genome Sequencing, Consortium
https://www.nature.com/articles/nature06784
2008
Tribolium castaneum is a member of the most species-rich eukaryotic order, a powerful model organism for the study of generalized insect development, and an important pest of stored agricultural products. We describe its genome sequence here. This omnivorous beetle has evolved the ability to interact with a diverse chemical environment, as shown by large expansions in odorant and gustatory receptors, as well as P450 and other detoxification enzymes. Development in Tribolium is more representative of other insects than is Drosophila, a fact reflected in gene content and function. For example, Tribolium has retained more ancestral genes involved in cell–cell communication than Drosophila, some being expressed in the growth zone crucial for axial elongation in short-germ development. Systemic RNA interference in T. castaneumfunctions differently from that in Caenorhabditis elegans, but nevertheless offers similar power for the elucidation of gene function and identification of targets for selective insect control.